Document modified with permission from the College of Physicians and Surgeons of Alberta
6. Driving
There is a risk I may become drowsy when starting opioid therapy or when the dose is increased.
I agree not to drive a motor vehicle or operate dangerous machinery until I am on a stable dose
and do not experience any drowsiness.
7. Use with other medications
I also understand that I may become very drowsy if I take opioid medication at the same time
with other medications that cause drowsiness (such as sedatives or sleeping pills) or with
alcohol. I will not take any of these without talking to my doctor first.
8. Medication complications
I understand that opioids may cause long-term complications, which may include decreased
hormones such as testosterone, unexpected increase in pain sensitivity, and changes in
breathing patterns while sleeping.
9. Addiction
I am aware that there is a small but real risk that I may become addicted to the prescribed
opioids. The risk of addiction is increased with a past or present history of substance or alcohol
use disorder, and prescribed opioids are often reported as a cause for relapse in recovering
patients. A history of substance use disorder does not preclude the use of opioids but warrants
increased pharmacovigilance. I know that my doctor may order a consultation with a specialist
in addiction medicine if there is a concern about addiction.
10. Adherence
I understand that my doctor may ask me for a urine drug screen sample or a count of my pills at
any time. This is performed routinely for all patients to improve the overall safety of using
opioids. Urine drug monitoring will also look for other substance use that increases the risks
associated with using opioids. Further refills/prescriptions will be tied to completion of urine
tests. Doctors and clinics are encouraged to consider a policy of random urines for all patients
on long-term opioid treatment that are not designated palliative or cancer patients.
11. Use of other medications
I will not use non-prescription medications containing codeine, such as Tylenol ® #1 or 222®
tablets. My doctor may request me to reduce the dose of medications (such as sleeping pills)
that increase my risk of harm when used in combination with an opioid.
12. Stopping medications and withdrawal symptoms
I understand that suddenly stopping or reducing the amount of opioid that I am taking may lead
to withdrawal symptoms. Initial symptoms may include runny nose, sweating, tearing of the
eyes, restlessness and/or diarrhea. Later symptoms may include anxiety, irritability, weakness,
twitching and muscle spasms, severe backache and abdominal pain, leg pains and cramps, hot
and cold flashes, sleeplessness, nausea, vomiting, slight fever, increased heart rate and blood
pressure. These symptoms can be minimized by slowly reducing the opioid dose and should only
be done under the direction of my doctor. If I have stopped taking my opioid medication for 3
days or more for any reason, I will not resume taking it without talking to my doctor.
13. Appointment attendance
I will attend all appointments, treatments and consultations as requested by my doctor.