PreVIcox~
~
---6-
mrocoxlb)
~
_,~
Information
for
Dog
Owners
about
PREVICOX®
(firocoxib)
Chewable
Tablets
PREVICOX
Chewable
Tablets
are
used
for
the
control
of
pain
and
inflammation
due
to
osteoarthritis
or
associated
with
soft-tissue
and
orthopedic
surgery
in
your
dog.
This
summary
contains
i
mportant
information
about
PREVICOX
.
You
should
read
this
information
before
you
start
giving
your
dog
PREVICOX
tablets
and
review
it
each
time
your
prescription
is
ref
i
lled
.
This
sheet
is
provided
only
as
a
summary
and
does
not
take
the
place
of
instructions
from
your
veterinarian
.
Talk
to
your
veterinarian
if
.
you
do
not
understand
any
of
this
information
or
you
want
to
know
more
about
PREVICOX.
What
is
PREVICOX?
PREVICOX
is
a
veterinary
prescription
non-steroidal
anti-inflammatory
drug
(NSAID)
used
to
control
pain
and
inflammation
due
to
osteoarthritis
,
or
associated
with
soft-tissue
and
orthopedic
surgery
in
dogs
.
Osteoarthritis
is
a
painful
condition
caused
by
"wear
and
tear"
of
cartilage
and
other
parts
of
the
joints
that
may
result
in
the
following
changes
or
signs
in
your
dog
:
•
Limping
or
lameness.
•
Decreased
activity
or
exercise
(re
l
uctance
to
stand
,
climb
stairs,
jump
or
run
,
or
difficulty
in
performing
these
activities).
•
Stiffness
or
decreased
movement
of
joints
.
PREVICOX
is
i
ndicated
for
the
control
of
postoperative
pain
and
inflammation
following
soft-tissue
and
orthoped
ic
surger
i
es
(e.g.
spays
,
cruciate
ligament
repair).
Your
veter
i
narian
may
administer
PREVICOX
before
the
procedure
and
recommend
that
the
dog
be
treated
for
a
few
days
after
going
home
.
What
kind
of
results
can
I
expect
when
my
dog
is
on
PREVICOX
for
osteoarthritis?
While
PREVICOX
is
not
a
cure
for
osteoarthritis,
it
can
control
the
pain
and
inflammat
i
on
and
improve
your
dog
's
mobility.
•
Response
varies
from
dog
to
dog,
but
improvement
can
be
quite
dramatic
.
•
In
most
dogs
,
improvement
can
be
seen
within
days
.
•
If
PREVICOX
is
discontinued
or
not
given
as
directed
,
your
dog's
pain
and
inflammation
may
return
.
What
kind
of
results
can
I
expect
when
my
dog
is
on
PREVICOX
for
the
control
of
pain
and
inflammation
following
son-tissue
and
orthopedic
surgery?
•
PREVICOX
Chewable
Tablets
allow
your
dog
to
recover
more
comfortably
by
controlling
pain
and
i
nflammation
following
soft-
tissue
and
orthopedic
surgery
.
•
Control
of
pa
in
and
i
nflammation
may
vary
from
dog
to
dog.
•
If
PREVICOX
Chewable
Tab
l
ets
are
not
given
according
to
your
veterinarian
's
directions
,
your
dog
's
pa
in
may
return
.
•
Consult
your
veterinarian
if
your
dog
appears
to
be
uncomfortable
.
Which
dogs
should
not
take
PREVICOX?
Your
dog
should
n
ot
be
gi
ven
PREVICOX
if
he
/
she
:
•
Has
an
allergic
reaction
to
firocoxib
,
the
active
i
ngredient
in
PREVICOX
.
•
Has
had
an
allergic
reaction
(such
as
hives,
facial
swelling,
or
red
or
itchy
skin)
to
aspirin
or
other
NSAIDs
.
•
Is
presently
taking
aspirin
,
other
NSAIDs,
or
corticosteroids.
•
Is
under
12
.5
pounds
in
body
weight.
•
Has
pre
-
existing
kidney
or
liver
disease
.
•
Has
decreased
appetite
,
vomiting
or
diarrhea
.
PREVICOX
should
only
be
given
to
dogs.
People
should
not
take
PREVICOX.
Keep
PREVICOX
and
a
ll
medicat
i
ons
out
of
the
reach
of
children
.
Call
your
physician
immediately
if
you
accidentally
take
PREVICOX
.
What
to
tell/ask
your
veterinarian
before
giving
PREVICOX.
Talk
to
your
veterinar
i
an
about
•
The
si
gns
of
osteoarthritis
you
have
observed
in
your
dog
,
such
as
limping
or
stiffness.
•
The
importance
of
weight
control
in
the
management
of
osteoarthritis
.
•
What
tests
might
be
done
before
PREVICOX
is
prescribed
.
•
How
often
your
dog
may
need
to
be
examined
by
your
veterinarian
.
•
The
ri
sks
and
benefits
of
using
PREVICOX
.
Serious
adverse
reactions
,
including
death
,
have
been
associated
with
PREVICOX
administration
at
doses
above
the
recommended
dose
in
puppies
less
than
seven
months
of
age
.
Tell
your
veterinarian
if
your
dog
is
currently
experienc
i
ng
or
has
ever
had
the
following
medica
l
problems
:
•
Any
side
effects
f
rom
taking
PREVI
Cox
or
other
N
S
AIDs
,
such
as
asp
i
rin
.
•
Any
digestive
upset
(vom
i
ting
and/or
diarrhea)
.
•
Any
ki
dney
disease
.
•
Any
liver
disease
.
Tell
your
veter
i
narian
about:
•
Any
other
medical
problems
or
allergies
that
your
dog
has
now,
or
has
had
in
the
past.
•
All
medicines
that
you
are
giving
or
plan
to
give
to
your
dog,
including
those
you
can
get
without
a
prescription
and
any
dietary
supplements
.
Tell
your
veterinarian
if
your
dog:
•
Is
under
7
months
of
age
.
•
Is
pregnant
,
nursing
or
if
you
plan
to
breed
your
dog.
How
to
give
PREVICOX
to
your
dog.
PREVICOX
should
be
given
according
to
your
veterinarian's
instructions.
Do
not
change
the
way
you
give
PREVICOX
to
your
dog
without
first
speaking
with
your
veterinarian.
Your
veterinarian
will
tell
you
what
amount
of
PREVICOX
is
right
for
your
dog
and
for
how
long
it
should
be
given
.
Most
dogs
will
take
PREVICOX
Chewable
Tablets
from
your
hand
,
or
you
can
place
the
tablet
in
your
dog
's
mouth
.
PREVICOX
may
be
given
with
or
without
food
.
What
are
the
possible
side
effects
that
may
occur
in
my
dog
during
PREVICOX
therapy?
PREVICOX,
like
other
NSAIDS,
may
cause
some
side
effects.
Serious
side
effects
associated
with
NSAID
therapy
in
dogs
can
occur
with
or
without
warning,
and,
in
rare
situations,
result
in
death.
The
most
common
side
effects
associated
with
PREVICOX
therapy
involve
the
digestive
tract
(vomiting
and
decreased
food
consumption).
Liver
and
kidney
problems
have
also
been
reported
with
NSAIDs.
Look
for
the
following
side
effects
that
may
indicate
your
dog
is
having
a
problem
with
PREVICOX:
•
Decrease
or
increase
in
appetite.
•
Vomiting
.
•
Change
in
bowel
movements
(such
as
diarrhea,
or
black,
tarry
or
bloody
stools)
.
•
Change
in
behavior
(such
as
decreased
or
increased
activity
level
,
incoordination
,
seizure,
or
aggression).
•
Yellowing
of
gums
,
skin,
or
whites
of
the
eyes
Oaundice).
•
Change
in
drinking
habits
(frequency
or
amount
consumed).
•
Change
in
urination
habits
(frequency,
color,
or
smeiQ.
•
Change
in
skin
(redness
,
scabs
,
or
scratching).
•
Unexpected
weight
loss
.
It
is
important
to
stop
the
medication
and
contact
your
veterinarian
immediately
if
you
think
your
dog
has
a
medical
problem
or
side
effect
wh
i
le
taking
PREVICOX
tablets.
~you
have
additional
questions
about
poss
i
ble
side
effects
,
talk
with
your
veterinarian
or
call
1-
877
-
217
-
3543
.
Can
PREVICOX
be
given
with
other
medications?
PREVICOX
should
not
be
given
with
other
NSAIDs
(for
example,
aspirin
,
carprofen
,
etodolac
,
deracoxib,
meloxicam,
or
tepoxalin)
or
corticosteroids
(for
example,
prednisone,
cortisone,
dexamethasone,
or
triamc
i
no
l
one)
.
Tell
your
veterinarian
about
all
medications
that
you
have
given
your
dog
in
the
past
,
and
any
med
i
cations
you
are
planning
to
give
with
PREVICOX
tablets
.
Th
is
should
include
other
medicines
that
you
can
get
without
a
prescription
or
any
dietary
supplements.
Your
veterinarian
may
want
to
check
that
all
of
your
dog's
medicines
can
be
given
together
.
What
do
I
do
in
case
my
dog
eats
more
than
the
prescribed
amount
of
PREVICOX?
Consult
your
veterinarian
immediately
if
your
dog
eats
more
than
the
prescribed
amount
of
PREVICOX
.
What
else
should
I
know
about
PREVICOX?
• T
hi
s
sheet
prov
i
des
a
summary
of
information
about
PREVICOX
tablets
.
If
you
have
any
questions
or
concerns
about
PREVICOX,
osteoarthr
iti
s
pain
,
or
postoperative
pain
following
soft-tissue
and
orthopedic
surgery
,
talk
with
your
veterinarian.
•
As
wi
th
all
prescribed
medicines,
PREVICOX
tablets
should
only
be
gi
ven
to
the
dog
for
which
they
were
prescribed.
They
should
be
given
to
your
dog
only
for
the
condition
for
which
they
were
prescribed
,
at
the
prescribed
dose
.
•
It
is
important
to
periodically
discuss
your
dog's
response
to
PREVICOX
tablets
.
Your
veterinarian
will
determine
if
your
dog
is
responding
as
expected
and
if
your
dog
should
continue
receiving
PREVICOX
tablets
.
For
technical
assistance
or
to
report
suspected
adverse
reactions,
call1-877
-217-3543.
N
AD
A 1
41-230,
Appro
ve
d by
FDA
©
2012
Me
ri
a
l.
All
R
ights
Re
s
erv
ed.
®PREVICOX
is
a
registe
r
ed
tra
dem
ark
of
Me
ri
a
l.
Rev.03-2012
